Drug rash with eosinophilia and systemic symptoms secondary to phenobarbitone

Agostino Baruzzi; Manuela Contin; Giovanni Barbara; Cesare Cremon; Roberto De Giorgio; Annalisa Patrizi; Fiorenzo Albani; Roberto Corinaldesi

doi:10.1097/00002826-200307000-00004

Drug rash with eosinophilia and systemic symptoms secondary to phenobarbitone

Clin Neuropharmacol. 2003 Jul-Aug;26(4):177-8. doi: 10.1097/00002826-200307000-00004.

Authors

Agostino Baruzzi¹, Manuela Contin, Giovanni Barbara, Cesare Cremon, Roberto De Giorgio, Annalisa Patrizi, Fiorenzo Albani, Roberto Corinaldesi

Affiliation

¹ Department of Neurological Sciences, Neurology Clinic, University of Bologna, Via Foscolo 7, 40123 Bologna, Italy.

PMID: 12897635
DOI: 10.1097/00002826-200307000-00004

Abstract

The authors describe a case of a rare, potentially fatal multisystem reaction, recently called drug rash with eosinophilia and systemic symptoms (or DRESS) resulting from phenobarbitone. They highlight the main characteristics of this syndrome and the diagnostic difficulties.

Publication types

Case Reports

MeSH terms

Adult
Eosinophilia / chemically induced*
Eosinophilia / complications
Eosinophilia / diagnosis
Exanthema / chemically induced*
Exanthema / complications
Exanthema / diagnosis
Female
Humans
Multiple Organ Failure / chemically induced*
Multiple Organ Failure / complications
Multiple Organ Failure / diagnosis
Phenobarbital / adverse effects*

Substances

Phenobarbital