[Description and prognostic value of cerebellar MRI lesions in children with severe acute ataxia]

Arch Pediatr. 2003 Jul;10(7):604-7. doi: 10.1016/s0929-693x(03)00273-2.
[Article in French]

Abstract

The aim of this work was to evaluate NMR cerebellar abnormalities in children with severe acute ataxia. Among 8 consecutively observed children, NMR performed in 6 during the acute phase was pathological in 4, demonstrating hyperintense signal in the T2-weighed sequences of dentate nuclei (2 cases, associated in 1 with hyperintense signal in the medium cerebellar peduncle) or of the cerebellar cortex associated with cerebellar swelling (2 cases). NMR performed in 7 cases after at least 1 month of evolution showed cerebellar atrophy in 4 cases. After 1 to 6 years of clinical follow-up, 4/8 children had clinical sequellae, including 3 of the 4 children with initially abnormal NMR. Conversely, the 2 patients with initially normal NMR had a good clinical recovery. NMR during the acute phase gives informations on prognosis in patients with severe acute ataxia.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Acute Disease
  • Atrophy
  • Cerebellar Ataxia / pathology*
  • Cerebellum / pathology*
  • Child
  • Child, Preschool
  • Female
  • Humans
  • Infant
  • Magnetic Resonance Imaging
  • Male
  • Prognosis