Abstract
The study included 24 cases of negative second-look laparotomy (SLL) after operation on ovarian cancer. 12 cases were treated with sizofiran and recombinant interferon-gamma before and after SLL and then with human lymphoblastoid interferon-alpha. The remaining 12 cases (controls) were followed up without any drug therapy after SLL. There were no recurrences in the treated group, but in 3 cases of the control group. Also significant difference in survival was noted in the treated group.
Publication types
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Clinical Trial
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Controlled Clinical Trial
MeSH terms
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Adult
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Aged
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Antineoplastic Combined Chemotherapy Protocols / therapeutic use*
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Chemotherapy, Adjuvant
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Combined Modality Therapy
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Female
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Humans
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Interferon-alpha / administration & dosage
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Interferon-gamma / administration & dosage
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Middle Aged
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Ovarian Neoplasms / drug therapy*
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Ovarian Neoplasms / surgery
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Recombinant Proteins
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Sizofiran / administration & dosage
Substances
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Interferon-alpha
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Recombinant Proteins
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Sizofiran
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Interferon-gamma