Synthesis of tetrasubstituted naphthalenes by palladium-catalyzed reaction of aryl iodides with internal alkynes

Satoshi Kawasaki; Tetsuya Satoh; Masahiro Miura; Masakatsu Nomura

doi:10.1021/jo0346656

Synthesis of tetrasubstituted naphthalenes by palladium-catalyzed reaction of aryl iodides with internal alkynes

J Org Chem. 2003 Aug 22;68(17):6836-8. doi: 10.1021/jo0346656.

Authors

Satoshi Kawasaki¹, Tetsuya Satoh, Masahiro Miura, Masakatsu Nomura

Affiliation

¹ Department of Applied Chemistry, Faculty of Engineering, Osaka University, Suita, Osaka 565-0871, Japan.

PMID: 12919062
DOI: 10.1021/jo0346656

Abstract

The 1:2 coupling of aryl iodides with acetylenedicarboxylate esters and diphenylacetylene efficiently proceeds in the presence of a palladium catalyst with use of silver carbonate as base to produce the corresponding tetrasubstituted naphthalenes.