Abstract
Clozapine is the least likely anti-psychotic to induce extrapyramidal symptoms (EPS). We present a surprising case of a woman schizophrenic patient treated with clozapine suffering from EPS. Single photon emission computed tomography (SPECT) revealed a low density of presynaptic dopamine transporters in our patient's brain. A comorbid diagnosis of Parkinson's disease in schizophrenia was confirmed in this way. This helped us to find a proper therapeutic strategy for our patient.
MeSH terms
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Antipsychotic Agents / adverse effects
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Antipsychotic Agents / therapeutic use*
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Brain / diagnostic imaging
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Clozapine / therapeutic use*
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Diagnosis, Differential
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Female
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Humans
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Middle Aged
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Parkinson Disease, Secondary / chemically induced
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Parkinson Disease, Secondary / diagnosis
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Parkinsonian Disorders / complications*
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Parkinsonian Disorders / diagnostic imaging
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Parkinsonian Disorders / psychology
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Recurrence
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Schizophrenia / complications*
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Schizophrenia / drug therapy*
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Schizophrenic Psychology
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Tomography, Emission-Computed, Single-Photon
Substances
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Antipsychotic Agents
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Clozapine