Magnetic resonance imaging of lymphomatoid granulomatosis: punctate and linear enhancement preceding hemorrhage

Eur Radiol. 2003 Sep;13(9):2192-5. doi: 10.1007/s00330-002-1657-y. Epub 2002 Oct 9.

Abstract

Lymphomatoid granulomatosis (LG) is an angiocentric and angiodestructive lymphoproliferative disease that mainly involves the lung. Thirty percent of patients with LG have neurological symptoms. We report serial changes in MRI of a patient with LG of the brain. Postcontrast MRI demonstrated multiple punctate and linear areas that preceded hemorrhage, as indicated by hypointensity with surrounding hyperintensity on subsequent T2-weighted images. The diagnostic value of these lesions observed with contrast MR images is discussed. We consider that enhancing areas correspond to walls of small vessels affected by LG.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Brain Diseases / complications
  • Brain Diseases / diagnosis*
  • Humans
  • Intracranial Hemorrhages / complications
  • Intracranial Hemorrhages / diagnosis
  • Lymphoma, T-Cell / diagnosis
  • Lymphomatoid Granulomatosis / complications
  • Lymphomatoid Granulomatosis / diagnosis*
  • Magnetic Resonance Imaging*
  • Male