The serums of different categories, those who are normal people and those who are patient suffering from nasopharyngeal cancer, liver cancer and chronic leukaemia, were determined by laser Raman spectra at the range of 0-2,000 cm-1. The results demonstrated that the serums of those who are suffering from the same disease show different characteristic peak height, but their Raman spectrogram characteristics are almost the same. There exists great difference in the laser Raman spectrogram for the serums of the different kinds of cancerous patients. Near the characteristic peaks of laser Raman spectrograms of serums from the cancerous patients, the normal person's serum has no Raman spectrogram characteristic peak.