[Association of the hSERT and SLC6A4 polymorphic markers of the serotonin transporter gene with schizophrenia in different ethnic groups]

A G Zaĭnullina; E B Iur'ev; S R Bikbulatova; E K Khusnutdinova

[Association of the hSERT and SLC6A4 polymorphic markers of the serotonin transporter gene with schizophrenia in different ethnic groups]

Mol Biol (Mosk). 2003 Jul-Aug;37(4):601-6.

[Article in Russian]

Authors

A G Zaĭnullina¹, E B Iur'ev, S R Bikbulatova, E K Khusnutdinova

Affiliation

¹ Institute of Biochemistry and Genetics, Ufa Research Center, Russian Academy of Sciences, Ufa, 450054 Russia.

PMID: 12942632

Abstract

Insertion/deletion and VNTR polymorphisms of the serotonin transporter gene were tested for association with schizophrenia in patients varying in ethnicity. A difference in genetic predisposition was observed for continuous and shift-like schizophrenia forms, the former tending to be associated with genotype 12/12 in Tatars and L/L in Russians.

Publication types

English Abstract

MeSH terms

Adolescent
Adult
Age of Onset
Bashkiria / ethnology
Carrier Proteins / genetics*
Carrier Proteins / metabolism
Case-Control Studies
Genetic Markers
Genetic Predisposition to Disease*
Homozygote
Humans
Membrane Glycoproteins / genetics*
Membrane Glycoproteins / metabolism
Membrane Transport Proteins*
Minisatellite Repeats
Nerve Tissue Proteins*
Polymorphism, Genetic
Schizophrenia / epidemiology
Schizophrenia / etiology
Schizophrenia / genetics*
Serotonin / metabolism
Serotonin Plasma Membrane Transport Proteins

Substances

Carrier Proteins
Genetic Markers
Membrane Glycoproteins
Membrane Transport Proteins
Nerve Tissue Proteins
SLC6A4 protein, human
Serotonin Plasma Membrane Transport Proteins
Serotonin