Splenic rupture as a consequence of dual malignant pathology: a case report

J Clin Pathol. 2003 Sep;56(9):709-10. doi: 10.1136/jcp.56.9.709.

Abstract

A 76 year old woman presented acutely with non-traumatic splenic rupture, which was successfully treated by emergency splenectomy. Histological examination of the spleen revealed the coexistence of metastatic adenocarcinoma cells, together with low grade B cell non-Hodgkin lymphoma. Splenic rupture as a consequence of malignant disease is discussed, together with a brief review of the literature.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Aged
  • Breast Neoplasms / complications*
  • Breast Neoplasms / pathology
  • Breast Neoplasms / secondary
  • Carcinoma, Lobular / complications*
  • Carcinoma, Lobular / pathology
  • Carcinoma, Lobular / secondary
  • Estrogen Antagonists / therapeutic use
  • Female
  • Humans
  • Lymphoma, B-Cell / complications*
  • Lymphoma, B-Cell / pathology
  • Lymphoma, B-Cell / surgery
  • Neoplasms, Multiple Primary / complications*
  • Neoplasms, Multiple Primary / pathology
  • Neoplasms, Multiple Primary / surgery
  • Rupture, Spontaneous
  • Splenectomy
  • Splenic Neoplasms / complications*
  • Splenic Neoplasms / pathology
  • Splenic Neoplasms / surgery
  • Splenic Rupture / etiology*
  • Splenic Rupture / pathology
  • Tamoxifen / therapeutic use

Substances

  • Estrogen Antagonists
  • Tamoxifen