Abstract
The complex architecture of bacterial biofilms inevitably raises the question of their design. Microstructure of developing Escherichia coli biofilms was analyzed under static and laminar flow conditions. Cell attachment during early biofilm formation exhibited periodic density patterns that persisted during development. Several models for the origination of biofilm microstructure are considered, including an activator-inhibitor or Turing model.
Publication types
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, Non-P.H.S.
MeSH terms
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Bacterial Adhesion / physiology*
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Biofilms / growth & development*
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Escherichia coli / physiology*
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Escherichia coli Proteins / genetics
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Escherichia coli Proteins / metabolism
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Models, Biological
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Periodicity*
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RNA-Binding Proteins / genetics
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RNA-Binding Proteins / metabolism
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Repressor Proteins / genetics
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Repressor Proteins / metabolism
Substances
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CsrA protein, E coli
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Escherichia coli Proteins
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RNA-Binding Proteins
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Repressor Proteins