[Importance of the role of dose rate on tumor induction in rats after radon inhalation]

C R Acad Sci III. 1992;315(12):463-6.
[Article in French]

Abstract

Lung cancer can be induced in rats, by radon daughter products, after exposure as low as 25 WLM (80 mJ.h.m-3) protracted over 4 to 6 months with a dose rate of 100 to 150 WL (2 to 3 mJ.m-3). The incidence of lung cancer is not increased and is equal to that of controls when the same cumulated dose is protracted over 18 months at 2 WL (0.042 mJ.m-3).

Publication types

  • English Abstract

MeSH terms

  • Administration, Inhalation
  • Animals
  • Dose-Response Relationship, Radiation
  • Lung Neoplasms / epidemiology
  • Lung Neoplasms / etiology*
  • Male
  • Neoplasms, Radiation-Induced / epidemiology
  • Neoplasms, Radiation-Induced / etiology*
  • Radon / administration & dosage*
  • Radon / adverse effects*
  • Rats
  • Rats, Sprague-Dawley

Substances

  • Radon