Genetic localization of Hao-1, blind-sterile (bs), and Emv-13 on mouse chromosome 2

Genomics. 1992 Feb;12(2):403-4. doi: 10.1016/0888-7543(92)90392-6.

Abstract

The blind-sterile (bs) mutation in the mouse was localized on Chromosome 2 between Hao-1 and Emv-13. N2 progeny from a backcross between congenic female 129.AKR-bs Emv-13 mice and (129.AKR-bs/bs x Mus musculus molossinus) F1 male mice were typed by analysis of isozyme variants for Hao-1, visible inspection for bs, and restriction fragment length polymorphism for Emv-13 and Emv-15. Comparison between markers on mouse Chromosome 2 and corresponding markers on human chromosomes suggest that the human homolog of bs will be located on 20q11-q13.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Alcohol Oxidoreductases / genetics
  • Animals
  • Blindness / genetics
  • Chromosome Mapping
  • Crosses, Genetic
  • Infertility, Male / genetics
  • Leukemia Virus, Murine / genetics
  • Male
  • Mice / genetics*
  • Mutation

Substances

  • Alcohol Oxidoreductases
  • L-2-hydroxyacid oxidase