Nucleotide sequences of normal and rearranged RNA segments 10 of human rotaviruses

J Gen Virol. 1992 Mar:73 ( Pt 3):633-8. doi: 10.1099/0022-1317-73-3-633.

Abstract

Normal and rearranged RNA segments 10 of group A rotaviruses isolated from a chronically infected immunodeficient child were amplified by the polymerase chain reaction as full-length cDNA copies, and were subsequently cloned and sequenced. Compared with the nucleotide sequence of the normal RNA segment 10, the rearranged form contains a partial non-coding duplication at its 3' end and several point mutations. The normal RNA segment 10 was similar to that of bovine rotavirus.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amino Acid Sequence
  • Base Sequence
  • Child
  • Child, Preschool
  • Cloning, Molecular
  • Genetic Variation
  • Humans
  • Molecular Sequence Data
  • Polymerase Chain Reaction
  • RNA, Viral / genetics*
  • Rotavirus / classification
  • Rotavirus / genetics*
  • Rotavirus Infections / genetics*
  • Sequence Homology, Nucleic Acid

Substances

  • RNA, Viral

Associated data

  • GENBANK/D01145
  • GENBANK/D01146
  • GENBANK/D10681
  • GENBANK/D10771
  • GENBANK/D10772
  • GENBANK/M65168
  • GENBANK/M65169
  • GENBANK/M65170
  • GENBANK/M65171
  • GENBANK/M65172
  • GENBANK/M65173
  • GENBANK/M65174