Purulent meningitis due to aspergillosis in a patient with systemic lupus erythematosus

Clin Neurol Neurosurg. 1992;94(1):39-43. doi: 10.1016/0303-8467(92)90117-l.

Abstract

We report a 39-year-old female patient with systemic lupus erythematosus under immunosuppressive therapy who developed persistent neutrophilic meningitis, for which no infectious agent could be identified. Intensifying the immunosuppressive therapy induced a short amelioration of the clinical picture. At autopsy, basal meningitis was found to be due to Aspergillus sp.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Aspergillosis / diagnosis*
  • Aspergillosis / pathology
  • Aspergillus / ultrastructure
  • Brain / pathology
  • Cerebral Infarction / diagnosis
  • Cerebral Infarction / pathology
  • Diagnosis, Differential
  • Female
  • Humans
  • Lupus Erythematosus, Systemic / diagnosis*
  • Lupus Erythematosus, Systemic / pathology
  • Magnetic Resonance Imaging
  • Meningitis, Fungal / diagnosis*
  • Meningitis, Fungal / pathology
  • Neurologic Examination
  • Opportunistic Infections / diagnosis*
  • Opportunistic Infections / pathology
  • Pseudotumor Cerebri / diagnosis
  • Pseudotumor Cerebri / pathology
  • Tomography, X-Ray Computed