Regulation of intracellular cyclic AMP concentrations in hepatocytes involves the integrated activation and desensitization of adenylyl cyclase coupled with the action and activation of specific isoforms of cyclic AMP phosphodiesterase

Biochem Soc Trans. 1992 Feb;20(1):140-6. doi: 10.1042/bst0200140.

Authors

M D Houslay¹, S L Griffiths, Y M Horton, C Livingstone, M Lobban, F Macdonald, N Morris, J Pryde, G Scotland, Y Shakur, et al.

Affiliation

¹ Department of Biochemistry, University of Glasgow, U.K.

PMID: 1321746
DOI: 10.1042/bst0200140

No abstract available

Publication types

Research Support, Non-U.S. Gov't
Review

MeSH terms

3',5'-Cyclic-AMP Phosphodiesterases / metabolism*
Adenylyl Cyclases / metabolism*
Animals
Cyclic AMP / metabolism*
Enzyme Activation
Homeostasis
Isoenzymes / metabolism*
Kinetics
Liver / metabolism*

Substances

Isoenzymes
Cyclic AMP
3',5'-Cyclic-AMP Phosphodiesterases
Adenylyl Cyclases