In vitro mutagenesis defines drug targets in aldolase of Plasmodium falciparum

Mem Inst Oswaldo Cruz. 1992:87 Suppl 3:263-4. doi: 10.1590/s0074-02761992000700043.
No abstract available

Publication types

  • Review

MeSH terms

  • Animals
  • Antimalarials / pharmacology*
  • Drug Design
  • Drug Resistance / genetics
  • Fructose-Bisphosphate Aldolase / antagonists & inhibitors*
  • Fructose-Bisphosphate Aldolase / genetics
  • Genes, Protozoan
  • Mutagenesis*
  • Plasmodium falciparum / drug effects
  • Plasmodium falciparum / enzymology*
  • Plasmodium falciparum / genetics
  • Protozoan Proteins / antagonists & inhibitors*
  • Protozoan Proteins / genetics
  • Rabbits
  • Recombinant Proteins / antagonists & inhibitors
  • Recombinant Proteins / genetics

Substances

  • Antimalarials
  • Protozoan Proteins
  • Recombinant Proteins
  • Fructose-Bisphosphate Aldolase