Linkage mapping of human chromosome 10 microsatellite polymorphisms

Genomics. 1992 Mar;12(3):604-6. doi: 10.1016/0888-7543(92)90455-2.

Abstract

Ten microsatellite DNA polymorphisms located on human chromosome 10 were regionally mapped using subchromosomal somatic cell hybrids and linkage analysis. The resulting order of the markers from pter-qter was [D10S89, D10S111], D10S107, D10S109, [D10S91, D10S110, D10S108, D10S88, D10S168], and D10S169. Order of the markers within brackets was uncertain, although the order given was most likely. The microsatellites were distributed along the chromosome from the proximal p arm to near qter, with an unlinked gap between D10S168 and D10S169.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Alleles
  • Base Sequence
  • Chromosome Mapping
  • Chromosomes, Human, Pair 10*
  • DNA, Satellite / genetics*
  • Genetic Linkage
  • Genotype
  • Heterozygote
  • Humans
  • Molecular Sequence Data
  • Oligodeoxyribonucleotides
  • Polymorphism, Genetic*
  • Polymorphism, Restriction Fragment Length

Substances

  • DNA, Satellite
  • Oligodeoxyribonucleotides