In vivo occupancy of dopamine receptors by antipsychotic drugs

Arch Gen Psychiatry. 1992 Jul;49(7):588-9. doi: 10.1001/archpsyc.1992.01820070082019.
No abstract available

Publication types

  • Letter

MeSH terms

  • Animals
  • Antipsychotic Agents / metabolism*
  • Antipsychotic Agents / pharmacology
  • Brain / drug effects
  • Brain / metabolism*
  • Clozapine / metabolism
  • Clozapine / pharmacology
  • Haloperidol / metabolism
  • Haloperidol / pharmacology
  • Humans
  • Rats
  • Receptors, Dopamine / drug effects
  • Receptors, Dopamine / metabolism*
  • Receptors, Serotonin / drug effects
  • Receptors, Serotonin / metabolism
  • Spiperone / analogs & derivatives
  • Spiperone / metabolism

Substances

  • Antipsychotic Agents
  • Receptors, Dopamine
  • Receptors, Serotonin
  • Spiperone
  • 3-N-methylspiperone
  • Clozapine
  • Haloperidol