Molecular studies on trypanothione reductase: an antiparasitic target enzyme

Curr Top Cell Regul. 1992:33:409-17. doi: 10.1016/b978-0-12-152833-1.50028-9.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Amino Acid Sequence
  • Animals
  • Antiprotozoal Agents / pharmacology
  • Binding Sites
  • Chagas Disease / epidemiology
  • Crithidia / enzymology
  • Drug Design
  • Glutathione / analogs & derivatives*
  • Glutathione / metabolism
  • Glutathione Reductase / metabolism
  • Leishmania / enzymology
  • Molecular Sequence Data
  • Mutagenesis, Site-Directed
  • NADH, NADPH Oxidoreductases / antagonists & inhibitors
  • NADH, NADPH Oxidoreductases / metabolism*
  • Oxidation-Reduction
  • Prevalence
  • Protein Engineering
  • Protozoan Proteins / antagonists & inhibitors
  • Protozoan Proteins / genetics
  • Protozoan Proteins / metabolism*
  • Spermidine / analogs & derivatives*
  • Spermidine / metabolism
  • Substrate Specificity
  • Trypanosoma / enzymology*
  • Trypanosoma congolense / enzymology
  • Trypanosoma congolense / genetics
  • Trypanosomiasis, African / epidemiology

Substances

  • Antiprotozoal Agents
  • Protozoan Proteins
  • trypanothione
  • NADH, NADPH Oxidoreductases
  • trypanothione reductase
  • Glutathione Reductase
  • Glutathione
  • Spermidine