Abstract
To determine the false-positivity of antibody to hepatitis C virus (HCV) (anti-C100-3), the correlation between ELISA optical density (OD), anti-HCV titer and recombinant immunoblot assay (RIBA) in 87 anti-HCV-positive sera was analyzed. The results showed that > 90% of the serum samples with an anti-HCV OD > 2.0 or with titers > 10 x were RIBA reactive. These findings are applicable in daily clinical practice.
Publication types
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Comparative Study
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Research Support, Non-U.S. Gov't
MeSH terms
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Adult
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Blood Donors
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Child
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Enzyme-Linked Immunosorbent Assay*
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Female
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Hepacivirus / immunology*
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Hepatitis Antibodies / analysis*
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Hepatitis C / diagnosis*
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Hepatitis C / immunology
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Hepatitis C Antibodies*
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Hepatitis, Chronic / diagnosis
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Hepatitis, Chronic / immunology
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Humans
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Immunoblotting*
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Pregnancy
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Reference Values
Substances
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Hepatitis Antibodies
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Hepatitis C Antibodies
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anti-C100-3