Abstract
An actinomycete identified as Streptomyces flavidovirens was found to produce a new cyclic hexadepsipeptide antibiotic, designated citropeptin. Citropeptin showed antitumor activity against P388 murine leukemia.
MeSH terms
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Animals
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Anti-Bacterial Agents*
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Antibiotics, Antineoplastic / isolation & purification*
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Cell Survival / drug effects
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Leukemia P388 / drug therapy
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Mice
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Molecular Structure
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Peptides*
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Peptides, Cyclic / isolation & purification
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Peptides, Cyclic / pharmacology
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Streptomyces / metabolism
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Tumor Cells, Cultured
Substances
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Anti-Bacterial Agents
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Antibiotics, Antineoplastic
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Peptides
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Peptides, Cyclic
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citropeptin