Crystal structure of nevirapine, a non-nucleoside inhibitor of HIV-1 reverse transcriptase, and computational alignment with a structurally diverse inhibitor

J Med Chem. 1992 Jan;35(1):201-2. doi: 10.1021/jm00079a029.
No abstract available

Publication types

  • Comparative Study

MeSH terms

  • Azepines / chemistry*
  • Azepines / pharmacology
  • Benzodiazepines / chemistry
  • Benzodiazepines / pharmacology
  • Binding Sites
  • Crystallography
  • HIV-1 / drug effects
  • HIV-1 / enzymology
  • Imidazoles / chemistry
  • Imidazoles / pharmacology
  • Models, Molecular
  • Molecular Conformation
  • Nevirapine
  • Pyridines / chemistry*
  • Pyridines / pharmacology
  • Reverse Transcriptase Inhibitors*
  • X-Ray Diffraction

Substances

  • Azepines
  • Imidazoles
  • Pyridines
  • Reverse Transcriptase Inhibitors
  • Benzodiazepines
  • R-82913
  • Nevirapine