Galanin inhibits sexual behavior in male rats

Eur J Pharmacol. 1992 Mar 17;213(1):87-90. doi: 10.1016/0014-2999(92)90236-w.

Abstract

Intracerebroventricular injection of galanin potently inhibited (0.5 micrograms/rat) or completely suppressed (5.0 micrograms/rat) copulatory activity in sexually experienced male rats, without producing any other obvious behavioral deficit. It is suggested that galanin, known to potently stimulate feeding behavior, may be involved in the inverse modulation of feeding and sexual behaviors.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Feeding Behavior / drug effects
  • Female
  • Galanin
  • Injections, Intraventricular
  • Male
  • Motor Activity / drug effects
  • Peptides / administration & dosage
  • Peptides / pharmacology*
  • Rats
  • Rats, Inbred Strains
  • Sexual Behavior, Animal / drug effects*

Substances

  • Peptides
  • Galanin