Abstract
A combination of clarithromycin, ciprofloxacin, and amikacin for the treatment of Mycobacterium avium-Mycobacterium intracellulare bacteremia was evaluated in 12 AIDS patients. Mycobacteremia cleared in all patients by 2 to 8 weeks of treatment, and symptoms resolved. Four patients died; all had negative blood cultures until death, and disseminated M. avium-M. intracellulare complex infection was not considered the primary cause of death.
MeSH terms
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Acquired Immunodeficiency Syndrome / complications*
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Adult
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Amikacin / administration & dosage
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Amikacin / therapeutic use*
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Bacteremia / complications
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Bacteremia / drug therapy*
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Cause of Death
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Ciprofloxacin / administration & dosage
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Ciprofloxacin / therapeutic use*
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Clarithromycin
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Drug Administration Schedule
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Drug Therapy, Combination / therapeutic use
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Erythromycin / administration & dosage
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Erythromycin / analogs & derivatives*
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Erythromycin / therapeutic use
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Female
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Humans
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Male
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Mycobacterium avium-intracellulare Infection / complications
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Mycobacterium avium-intracellulare Infection / drug therapy*
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Pilot Projects
Substances
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Ciprofloxacin
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Erythromycin
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Amikacin
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Clarithromycin