[New packing of B-DNA in crystals]

Mol Biol (Mosk). 1992 May-Jun;26(3):573-82.
[Article in Russian]

Abstract

Two crystal forms of the self-complementary tetramer GpGpCpC have been obtained by phase diagram technique: P6(2)22/P6(4)22. a = b = 67.7 A, c = 105.6 A and P3(2)12/P3(1)12, a = b = 116.9 A. c = 116.4 A. Both crystals form diffract at least up to 3.2 A. Diffraction patterns of both crystal forms have strongest base-stacking reflections corresponding to the Bragg spacing 3.38 A which is typical for B-DNA. Moreover the self-rotation function of the first crystal form shows regular located two-fold pseudo-axes periodicity of which also indicates that this is B-conformation. The same conclusion can be reached on the basis of the crystal packing of the duplexes in the unit cell. It should be emphasized that this is a new example of B-DNA crystal packing.

Publication types

  • English Abstract

MeSH terms

  • Crystallization
  • DNA / chemistry*
  • Nucleic Acid Conformation
  • X-Ray Diffraction

Substances

  • DNA