[Radical surgery for ovarian cancer]

Gan To Kagaku Ryoho. 1992 Oct;19(12):1977-81.
[Article in Japanese]

Abstract

Mortality rate of ovarian cancer is increasing in Japan and the management of advanced cases is an important issue in order to improve long term survival. Radical surgery including systematic lymphadenectomy (LNX) from paraaortic nodes through pelvic nodes was, therefore, performed in our department with regular surgery (TAH, BSO, omentectomy) and lymph node metastasis (LNM) was analyses. LNM rate of patients whose LNX done in the primary surgery according to pTNM classification was as follows: pT1: 9.7%, pT2: 1.1%, pT3: 66.7% and that of those LNX done at SLO was as follows: pT1: 8.3%, pT2: 0%, pT3: 69.2%. Since radical surgery improved prognosis of advanced ovarian cancer significantly radical surgery including LNX are strongly recommended as a treatment of advanced ovarian cancer.

Publication types

  • English Abstract

MeSH terms

  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use
  • Chemotherapy, Adjuvant
  • Cisplatin / administration & dosage
  • Cyclophosphamide / administration & dosage
  • Doxorubicin / administration & dosage
  • Female
  • Humans
  • Lymph Node Excision*
  • Lymphatic Metastasis
  • Omentum / surgery
  • Ovarian Neoplasms / drug therapy
  • Ovarian Neoplasms / pathology
  • Ovarian Neoplasms / surgery*
  • Ovariectomy / methods*
  • Prognosis
  • Reoperation

Substances

  • Doxorubicin
  • Cyclophosphamide
  • Cisplatin

Supplementary concepts

  • CISCA protocol