Dose-titration to confirm the level of fenbendazole for control of Raillietina cesticillus in broiler chickens

Avian Dis. 1992 Jul-Sep;36(3):722-4.

Abstract

A total of 452 broiler chickens, naturally infected with Raillietina cesticillus, were allotted into six treatment groups. One group was fed unmedicated broiler ration (Group 1), and the other five groups were fed broiler ration containing fenbendazole at 180 ppm for 3 days (38.5 mg/kg body weight [BW]), 240 ppm for 3 days (50.9 mg/kg BW), 120 ppm for 6 days (52.2 mg/kg BW), 180 ppm for 6 days (79.9 mg/kg BW), or 240 ppm for 6 days (104.3 mg/kg BW). Fenbendazole was 100.0% efficacious against R. cesticillus when administered in the diet at 240 ppm for 6 days; 99.9% at 240 ppm for 3 days and at 180 ppm for 6 days; 99.5% at 120 ppm for 6 days; and 96.9% at 180 ppm for 3 days. Fenbendazole treatment had no adverse effect on weight gain or feed intake.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Cestode Infections / drug therapy
  • Cestode Infections / veterinary*
  • Chickens / parasitology*
  • Dose-Response Relationship, Drug
  • Fenbendazole / administration & dosage*
  • Fenbendazole / therapeutic use
  • Poultry Diseases / drug therapy*
  • Poultry Diseases / parasitology

Substances

  • Fenbendazole