[Effects of artificial cultured Panax notoginseng cell on cardiovascular system]

Zhongguo Zhong Yao Za Zhi. 1992 Jun;17(6):361-3, 384.
[Article in Chinese]

Abstract

Alcoholic extract from artificial cultured Panax notoginseng cell (SCC) ip has been found conducive to increasing the resistance of mice to anoxia. In vitro it helps to increase the outflow of coronary vessels, decrease the heart rate, inhibit the constriction of aortic strip stimulated by nor-epinephrine and relax spasmodic constriction of ileum smooth muscles markedly. SCC powder suspension on po administration can contract bleeding and coagulation time. The pharmacologic activities of SCC are similar to those of crude Panax notoginseng.

MeSH terms

  • Animals
  • Aorta / drug effects
  • Cells, Cultured
  • Coronary Circulation / drug effects*
  • Culture Techniques
  • Drugs, Chinese Herbal / pharmacology*
  • Drugs, Chinese Herbal / therapeutic use
  • Female
  • Guinea Pigs
  • Heart Rate / drug effects
  • Hemostasis / drug effects
  • Hypoxia / drug therapy
  • Ileum / drug effects
  • Male
  • Mice
  • Muscle Contraction / drug effects*
  • Muscle, Smooth / drug effects
  • Muscle, Smooth, Vascular / drug effects*
  • Plants, Medicinal / cytology*
  • Rabbits
  • Rats

Substances

  • Drugs, Chinese Herbal