[Stability and chemosensitivity of Plasmodium falciparum to chloroquine in 1990 and 1991 in Ankazobe, a village in high plateau Madagascar]

P Ringwald; P Rabarison; L Raharimalala; M D Rason; J P Lepers; J Le Bras; J Roux

[Stability and chemosensitivity of Plasmodium falciparum to chloroquine in 1990 and 1991 in Ankazobe, a village in high plateau Madagascar]

Bull Soc Pathol Exot. 1992;85(3):219-22; discussion 222-3.

[Article in French]

Authors

P Ringwald¹, P Rabarison, L Raharimalala, M D Rason, J P Lepers, J Le Bras, J Roux

Affiliation

¹ Unité de Recherche sur le Paludisme, Institut Pasteur de Madagascar, Antananarivo.

PMID: 1422272

Abstract

The in vivo and in vitro response of Plasmodium falciparum to chloroquine was conducted in Ankazobe, a village located in the high plateau area. These studies confirmed the low level of chloroquine-resistance. The in vivo data indicate the absence of increase resistance during the 2 years study. Chloroquine is still the drug of choice for the treatment of malaria attack in this area.

Publication types

English Abstract
Research Support, Non-U.S. Gov't

MeSH terms

Animals
Chloroquine / pharmacology*
Chloroquine / therapeutic use
Drug Resistance
Humans
Madagascar
Malaria, Falciparum / drug therapy
Malaria, Falciparum / parasitology
Plasmodium falciparum / drug effects*

Substances

Chloroquine