[Pregnancy after renal transplantation. 27 patients and review of the literature]

J Gynecol Obstet Biol Reprod (Paris). 1992;21(6):683-9.
[Article in French]

Abstract

We report the course and outcome of 30 pregnancies in 27 renal transplant patients between 1970 and 1988. Delay between transplantation and pregnancy was 7.3 +/- 4.8 years. There were 1 twin pregnancy and 3 successive pregnancies. Immunosuppressive regime was prednisone and azathioprine in 28 cases and cyclosporine in 2. Hypertension (33%), preterm delivery (74%) and premature rupture of the membranes (33%) were the main complication encountered. The cesarean section rate was 73%, mainly because of these complications. Twenty-seven patients delivered of 31 healthy children. There was no congenital anomaly. Mean birth weight was 2.640 +/- 645 g. In utero growth retardation occurred in 7 cases (23%). Pregnancy after renal transplantation is of good prognosis for both the mother and child but the course of pregnancy can be complicated by hypertension, preterm birth and growth retardation.

Publication types

  • English Abstract

MeSH terms

  • Adult
  • Azathioprine / therapeutic use
  • Birth Weight
  • Cesarean Section / statistics & numerical data
  • Cyclosporine / therapeutic use
  • Drug Therapy, Combination
  • Female
  • Fetal Growth Retardation / epidemiology
  • Fetal Growth Retardation / etiology
  • Follow-Up Studies
  • France / epidemiology
  • Humans
  • Hypertension / epidemiology
  • Hypertension / etiology
  • Kidney Transplantation* / immunology
  • Kidney Transplantation* / physiology
  • Obstetric Labor, Premature / epidemiology
  • Obstetric Labor, Premature / etiology
  • Prednisone / therapeutic use
  • Pregnancy
  • Pregnancy Complications / epidemiology*
  • Pregnancy Complications / etiology
  • Pregnancy Outcome*
  • Prognosis
  • Risk Factors

Substances

  • Cyclosporine
  • Azathioprine
  • Prednisone