Abstract
We describe 7 Achilles tendinitis occurring during fluoroquinolone treatment. Antibiotic agents used were pefloxacin and ofloxacin. In 3 cases the course was complicated by rupture of the tendon, one of which is histologically documented. The toxic effects of quinolones on tendon is discussed.
MeSH terms
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Achilles Tendon / injuries*
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Achilles Tendon / pathology*
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Aged
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Aged, 80 and over
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Anti-Infective Agents / adverse effects*
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Anti-Infective Agents / therapeutic use
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Bronchitis / drug therapy
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Cystitis / drug therapy
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Female
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Humans
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Male
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Middle Aged
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Ofloxacin / therapeutic use
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Pefloxacin / therapeutic use
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Rupture, Spontaneous / chemically induced
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Spondylitis / drug therapy
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Tendinopathy / complications*
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Tendinopathy / pathology
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Tendon Injuries / complications*
Substances
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Anti-Infective Agents
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Pefloxacin
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Ofloxacin