This position statement is for general information and discussion only and is not intended as medical advice. Its purpose is to review the current literature on a controversial subject so as to assist medical practitioners who have an interest in pain management. The epidural injection of depot corticosteroids is one of a number of treatment techniques for chronic pain, and it is the view of the directors of the Australian Pain Society Limited that patients with chronic pain require assessment and treatment within multidisciplinary pain management programs. This statement does not encourage or discourage medical practitioners from using epidural steroid injections as a treatment modality. While this review of the pertinent literature may be of assistance to practitioners, no responsibility can be accepted by the Australian Pain Society Limited, or its directors, for any inaccuracy contained in studies referred to therein. All liability is expressly disclaimed for any loss or damage which may arise from any person acting on any statement or information contained herein.