Preiser's disease: identification of two patterns

J Hand Surg Am. 2003 Sep;28(5):767-78. doi: 10.1016/s0363-5023(03)00260-0.

Abstract

Purpose: A large series of patients with Preiser's disease was reviewed to compare 2 potentially different categories of this disorder: complete versus partial vascular impairment of the scaphoid bone as determined by magnetic resonance imaging (MRI).

Methods: Nineteen patients with Preiser's disease were identified retrospectively from 2 institutions. Using MRI criteria, 2 disease patterns were identified: diffuse necrosis and/or ischemia of the scaphoid (type 1 disease, 11 cases) and segmental vascular impairment of the scaphoid (type 2 disease, 8 cases). Risk factors for osteonecrosis, treatment methods, and serial radiographs were reviewed in all cases. Sixteen patients were examined for the purpose of this study at an average follow-up of 25 months.

Results: MRI signal changes of necrosis and/or ischemia involved 100% of the scaphoid in type 1 cases and on average approximately 42% in type 2 cases (range, 33% to 66%). In type 1 cases, regardless of the treatment used, the scaphoid typically fragmented and collapsed. In type 2 cases, scaphoid architecture was altered minimally after similar treatment methods. A history of wrist trauma was significantly more common in type 2 cases, and the results of treatment were generally better in this group of patients (mean Mayo modified wrist scores, 86 vs 58 points).

Conclusions: This study supports the concept of 2 patterns of scaphoid involvement in Preiser's disease. Type 1 cases are characterized by MRI signal changes of necrosis and/or ischemia involving the entire scaphoid bone. Patients in this group have a propensity for scaphoid deterioration. Type 2 cases have MRI signal changes involving only part of the scaphoid. These patients commonly report a history of wrist trauma, show fewer tendencies toward scaphoid fragmentation, and may have a more favorable clinical outcome.

MeSH terms

  • Adult
  • Disease Progression
  • Female
  • Humans
  • Ischemia / diagnosis*
  • Magnetic Resonance Imaging
  • Male
  • Middle Aged
  • Osteonecrosis / diagnosis*
  • Radiography
  • Retrospective Studies
  • Risk Factors
  • Scaphoid Bone / blood supply*
  • Scaphoid Bone / diagnostic imaging
  • Scaphoid Bone / pathology*
  • Treatment Outcome