Gadolinium-enhanced MR angiography as first-line preoperative imaging in high-risk patients with lower limb ischemia

J Vasc Interv Radiol. 2003 Sep;14(9 Pt 1):1139-45. doi: 10.1097/01.rvi.0000086533.86489.de.

Abstract

Purpose: To assess the clinical relevance of gadolinium-enhanced MR angiography (Gd-MRA) as the first-line angiographic examination for planning lower limb revascularization in patients at high risk of complications after contrast arteriography (CA).

Method: Forty-five consecutive patients at high risk of post-CA complications because of chronic renal insufficiency, diabetes mellitus, advanced age, or the need for brachial artery catheterization or graft puncture had Gd-MRA as first-line angiography before a surgical or endovascular procedure for lower limb ischemia.

Results: After Gd-MRA, 59 procedures were performed, including 38 surgical reconstructions, 17 endovascular procedures, and four amputations. Complementary CA was only required in seven patients for whom a below-knee bypass was planned. Cumulative patency rates at 1 and 24 months were, respectively, 91% and 91% for suprainguinal bypasses, 100% and 92% for infrainguinal above-knee bypasses, 80% and 57% for below-knee bypasses, and 92% and 76% for iliofemoral angioplasties. After 24 months of follow-up, limb salvage, amputation, and mortality rates were, respectively, 86%, 3.5%, and 7% for stage II ischemia and 48%, 11%, and 30% for stages III and IV.

Conclusion: Gd-MRA can be proposed for first-line preoperative imaging in the management of lower limb ischemia for patients at high risk and permits the selective use of CA as a second-line examination if a below-knee bypass is required.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Contrast Media
  • Female
  • Gadolinium DTPA*
  • Humans
  • Intraoperative Period
  • Ischemia / diagnosis*
  • Leg / blood supply*
  • Magnetic Resonance Angiography / methods*
  • Male
  • Middle Aged
  • Retrospective Studies
  • Risk Factors

Substances

  • Contrast Media
  • Gadolinium DTPA