Skin reactivity to metallic cobalt in patients with a positive patch test to cobalt chloride

Contact Dermatitis. 1992 Oct;27(4):241-3. doi: 10.1111/j.1600-0536.1992.tb03253.x.

Abstract

458 consecutive patients were patch tested with a metallic cobalt disc as a supplement to the standard series. 23 patients had a positive reaction to CoCl2 1% pet. Of these, 19 were tested with the cobalt disc. 11 had a positive reaction and 5 a questionable reaction. There were no positive reactions to the cobalt disc in patients with a negative patch test to CoCl2 1% pet. Patch testing with CoCl2 1% pet. diagnoses all patients with allergy to metallic cobalt, but the test method is limited by a high number of irritant and questionable reactions.

MeSH terms

  • Cobalt / adverse effects*
  • Dermatitis, Allergic Contact / diagnosis*
  • Dermatitis, Allergic Contact / etiology
  • False Positive Reactions
  • Female
  • Humans
  • Male
  • Patch Tests*

Substances

  • Cobalt
  • cobaltous chloride