Amplification of AML1 in acute lymphoblastic leukemia is associated with a poor outcome

Leukemia. 2003 Nov;17(11):2249-50. doi: 10.1038/sj.leu.2403140.

Authors

H M Robinson, Z J Broadfield, K L Cheung, L Harewood, R L Harris, G R Jalali, M Martineau, A V Moorman, K E Taylor, S Richards, C Mitchell, C J Harrison

PMID: 14523475
DOI: 10.1038/sj.leu.2403140

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Child
Child, Preschool
Core Binding Factor Alpha 2 Subunit
DNA-Binding Proteins / genetics*
Disease-Free Survival
Gene Amplification
Humans
Immunophenotyping
Neoplasm Proteins / genetics
Precursor Cell Lymphoblastic Leukemia-Lymphoma / genetics*
Precursor Cell Lymphoblastic Leukemia-Lymphoma / mortality
Prognosis
Proto-Oncogene Proteins*
Time Factors
Transcription Factors / genetics*
Treatment Outcome

Substances

Core Binding Factor Alpha 2 Subunit
DNA-Binding Proteins
Neoplasm Proteins
Proto-Oncogene Proteins
RUNX1 protein, human
Transcription Factors