Biochemical assessment of the early liver graft function in relation to selected donor parameters

Transplant Proc. 2003 Sep;35(6):2256-9. doi: 10.1016/s0041-1345(03)00809-1.

Abstract

The aim of this study was to assess the usefulness of liver grafts procured from "marginal donors." Among 62 liver transplants in 2002, almost half were harvested from donors who were not deemed acceptable by other transplant units. The authors compared the data concerning the donor's status with the function of the transplanted liver. The relations between individual parameters were estimated, as well as the differences between two groups of recipients: those who received a graft from the "poorer" donors versus those who received "better" grafts. Regardless of the relations between particular parameters a statistical analysis revealed that differences of liver function that were detected during the first 5 days after transplantation disappeared thereafter.

MeSH terms

  • Alanine Transaminase / blood
  • Alkaline Phosphatase / blood
  • Aspartate Aminotransferases / blood
  • Bilirubin / blood
  • Creatinine / blood
  • Humans
  • L-Lactate Dehydrogenase / blood
  • Liver Transplantation / physiology*
  • Patient Selection
  • Postoperative Period
  • Prothrombin Time
  • Time Factors
  • Tissue Donors / statistics & numerical data*
  • Treatment Outcome
  • Urea / blood

Substances

  • Urea
  • Creatinine
  • L-Lactate Dehydrogenase
  • Aspartate Aminotransferases
  • Alanine Transaminase
  • Alkaline Phosphatase
  • Bilirubin