Volume effect on sensitivity of nucleic acid amplification tests for detection of Chlamydia trachomatis in urine specimens from females

J Clin Microbiol. 2003 Oct;41(10):4842-3. doi: 10.1128/JCM.41.10.4842-4843.2003.

Abstract

Nucleic acid amplification tests (NAATs) for the detection of Chlamydia trachomatis are routinely used on first-catch urine (FCU) specimens. We analyzed data from a head-to-head comparison of NAATs on female FCU specimens and found that the volume of urine collected could affect test performance.

Publication types

  • Evaluation Study
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Chlamydia Infections / microbiology
  • Chlamydia trachomatis / genetics
  • Chlamydia trachomatis / isolation & purification*
  • Female
  • Humans
  • Nucleic Acid Amplification Techniques*
  • Sensitivity and Specificity
  • Specimen Handling / methods*
  • Urine / microbiology*