Objective: To study the adsorption and desorption behavior of macroporous adsorbption resin AB-8 for glycyrrhizic acid and its effect factors.
Methods: The optimum purification conditions were investigated by high performance liquid chromatography and the orthogonal experiments.
Results: The optimum conditions were as follows: the flow rate at 1 ml/min, pH at 6.4-7.4 and the solution concentration at 10 mg/ml.
Conclusion: AB-8 had a high adsorption capacity for glycyrrizic acid and elution was easy.