Abstract
A volumetric analysis by 3-dimensional intravascular ultrasound revealed that lipid-lowering therapy with pravastatin significantly reduced coronary plaque volume. The changes in plaque volume were inversely correlated with the changes in plasma levels of high-density lipoprotein cholesterol but not with changes in levels of total cholesterol or low-density lipoprotein cholesterol.
MeSH terms
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Adult
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Aged
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Aged, 80 and over
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Cholesterol, HDL / blood
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Cholesterol, HDL / drug effects*
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Cholesterol, LDL / blood
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Cholesterol, LDL / drug effects*
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Coronary Artery Disease / blood
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Coronary Artery Disease / diagnostic imaging
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Coronary Artery Disease / drug therapy*
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Coronary Vessels / diagnostic imaging*
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Female
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Humans
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Hydroxymethylglutaryl-CoA Reductase Inhibitors / therapeutic use*
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Imaging, Three-Dimensional
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Male
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Middle Aged
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Pravastatin / therapeutic use*
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Treatment Outcome
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Ultrasonography, Interventional
Substances
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Cholesterol, HDL
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Cholesterol, LDL
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Hydroxymethylglutaryl-CoA Reductase Inhibitors
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Pravastatin