Assessment of left ventricular function using solid-state gamma camera equipped with a highly-sensitive collimator

Ann Nucl Med. 2003 Sep;17(6):517-20. doi: 10.1007/BF03006446.

Abstract

Purpose: The solid-state gamma camera 2020tc Imager (Digirad, CA) is now commercially available and has been clinically applied. The present study evaluates the feasibility of equilibrium radionuclide ventriculography (ERNV) within a 3 min period using this camera equipped with a highly sensitive collimator.

Materials and methods: ERNV was performed from the best septal position (left anterior oblique view) in 20 patients with cardiac disease using a single detector anger-type gamma camera equipped with a low-energy, high-resolution collimator. Immediately thereafter, we performed a second ERNV using the solid-state gamma camera equipped with a highly sensitive collimator. Acquisition periods were 10 and 3 min, respectively.

Results: Significantly more counts were collected from over the left ventricle with the solid-state gamma camera over 3 min than those with the anger-type gamma camera over 10 min (817.1 +/- 387.8 k counts vs. 668.2 +/- 327.4 k counts, p < 0.01). The left ventricular ejection fraction obtained from ERNV data using the solid-state gamma camera correlated closely with those acquired by the anger-type gamma camera (r = 0.94, p < 0.0001, SEE = 5.93%).

Conclusion: The results showed that the solid-state gamma camera could assess left ventricular function with excellent data collection efficiency and high reliability.

Publication types

  • Clinical Trial
  • Comparative Study
  • Research Support, Non-U.S. Gov't
  • Validation Study

MeSH terms

  • Equipment Failure Analysis*
  • Feasibility Studies
  • Female
  • Gamma Cameras*
  • Humans
  • Male
  • Middle Aged
  • Radionuclide Imaging / instrumentation*
  • Radionuclide Imaging / methods*
  • Reproducibility of Results
  • Semiconductors
  • Sensitivity and Specificity
  • Stroke Volume
  • Transducers
  • Ventricular Dysfunction, Left / diagnosis
  • Ventricular Dysfunction, Left / diagnostic imaging*