Intravesicular administration of clotrimazole for treatment of candiduria in a cat with diabetes mellitus

J Am Vet Med Assoc. 2003 Oct 15;223(8):1156-8, 1129. doi: 10.2460/javma.2003.223.1156.

Abstract

A 12-year-old spayed female domestic longhair cat developed fungal cystitis (Candida sp). The cat had a history of chronic diabetes mellitus, hyperadrenocorticism, and bacterial cystitis caused by Escherichia coli. Antifungal agents (itraconazole and fluconazole) were administered orally without noticeable effect on the candiduria. Because of the ineffectiveness of these treatments, intravesicular administration of 1% clotrimazole solution was performed weekly for 3 treatments. Complete resolution of urinary candidiasis was detected after the third infusion. Intravesicular administration of clotrimazole solution appears to be a safe and effective treatment of fungal cystitis in cats.

Publication types

  • Case Reports

MeSH terms

  • Administration, Intravesical
  • Adrenalectomy / veterinary
  • Adrenocortical Hyperfunction / complications
  • Adrenocortical Hyperfunction / surgery
  • Adrenocortical Hyperfunction / veterinary
  • Animals
  • Antifungal Agents / administration & dosage
  • Antifungal Agents / therapeutic use*
  • Candidiasis / drug therapy
  • Candidiasis / urine
  • Candidiasis / veterinary*
  • Cat Diseases / drug therapy*
  • Cat Diseases / microbiology
  • Cat Diseases / urine
  • Cats
  • Clotrimazole / administration & dosage
  • Clotrimazole / therapeutic use*
  • Cystitis / drug therapy
  • Cystitis / microbiology
  • Cystitis / veterinary*
  • Diabetes Complications
  • Diabetes Mellitus / veterinary
  • Escherichia coli Infections / complications
  • Escherichia coli Infections / veterinary
  • Female
  • Treatment Outcome

Substances

  • Antifungal Agents
  • Clotrimazole