In vivo evaluation of plasma sprayed hydroxyapatite coatings having different crystallinity

Biomaterials. 2004 Feb;25(3):415-21. doi: 10.1016/s0142-9612(03)00545-3.

Abstract

In this paper, hydroxyapatite (HA) coatings having the crystallinities of 56% and 98% were deposited by the plasma spraying and vapor-flame treatment process. The phase composition and crystallinity of the coatings were investigated by X-ray diffraction and infrared spectra. The dissolution behavior of the coatings in tris-buffer solutions was examined. The results obtained indicated that the coating having the high crystallinity showed the lower dissolution as compared to the low crystallinity coating. The bone bonding ability of HA coatings were observed in vivo by implanted in dog's femur. After 3 months implantation, the high crystallinity coating showed the higher shear strengths and remained integrated, whereas the separation of the coating fragments was clearly observed in the coating having low crystallinity.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Biocompatible Materials / chemistry
  • Bone Substitutes
  • Buffers
  • Coated Materials, Biocompatible / chemistry*
  • Crystallization
  • Dogs
  • Durapatite / chemistry*
  • Femur / pathology
  • Materials Testing
  • Microscopy, Electron, Scanning
  • Surface Properties
  • Tensile Strength
  • Time Factors
  • X-Ray Diffraction

Substances

  • Biocompatible Materials
  • Bone Substitutes
  • Buffers
  • Coated Materials, Biocompatible
  • Durapatite