Optimizing levodopa pharmacokinetics in Parkinson's disease: the role of COMT inhibitor

Neurol Sci. 2003 Oct;24(3):217-8. doi: 10.1007/s10072-003-0138-7.
No abstract available

Publication types

  • Comparative Study

MeSH terms

  • Catechols / pharmacology*
  • Catechols / therapeutic use
  • Dopamine Agents / blood
  • Dopamine Agents / pharmacokinetics*
  • Drug Interactions
  • Drug Therapy, Combination
  • Enzyme Inhibitors / pharmacology*
  • Enzyme Inhibitors / therapeutic use
  • Half-Life
  • Humans
  • Levodopa / blood
  • Levodopa / pharmacokinetics*
  • Nitriles
  • Parkinson Disease / blood
  • Parkinson Disease / drug therapy
  • Parkinson Disease / metabolism*
  • Time Factors

Substances

  • Catechols
  • Dopamine Agents
  • Enzyme Inhibitors
  • Nitriles
  • Levodopa
  • entacapone