Successful treatment of vancomycin resistant Enterococcus faecium mediastinitis associated with left ventricular assist devices

Preeti N Malani; David B S Dyke; Francis D Pagani; Wendy S Armstrong; Carol E Chenoweth

doi:10.1016/s0003-4975(03)00560-5

Successful treatment of vancomycin resistant Enterococcus faecium mediastinitis associated with left ventricular assist devices

Ann Thorac Surg. 2003 Nov;76(5):1719-20. doi: 10.1016/s0003-4975(03)00560-5.

Authors

Preeti N Malani¹, David B S Dyke, Francis D Pagani, Wendy S Armstrong, Carol E Chenoweth

Affiliation

¹ Department of Internal Medicine, University of Michigan Health System, Ann Arbor, Michigan, USA.

PMID: 14602322
DOI: 10.1016/s0003-4975(03)00560-5

Abstract

We present 2 cases of vancomycin-resistant Enterococcus faecium mediastinitis associated with left ventricular assist devices in the setting of heart transplantation. Despite complicated operative courses and deep infection secondary to antimicrobial resistant organisms, both patients were successfully treated and have remained infection free in the long term.

Publication types

Case Reports

MeSH terms

Adult
Anti-Bacterial Agents*
Cardiomyopathy, Dilated / diagnosis
Cardiomyopathy, Dilated / surgery
Drug Therapy, Combination / therapeutic use*
Enterococcus faecium / drug effects*
Enterococcus faecium / isolation & purification
Female
Follow-Up Studies
Gram-Positive Bacterial Infections / drug therapy*
Gram-Positive Bacterial Infections / microbiology
Heart Transplantation
Heart-Assist Devices / adverse effects*
Humans
Male
Mediastinitis / drug therapy*
Mediastinitis / microbiology
Microbial Sensitivity Tests
Middle Aged
Postoperative Complications / drug therapy
Postoperative Complications / microbiology
Treatment Outcome
Vancomycin Resistance*

Substances

Anti-Bacterial Agents