Impaired hemodynamics and neural activation? A fMRI study of major cerebral artery stenosis

Neurology. 2003 Nov 11;61(9):1276-9. doi: 10.1212/01.wnl.0000092020.78323.5e.

Abstract

Functional MRI motor mapping was performed in two women with unilateral high-grade stenosis of the middle cerebral artery (MCA) to determine the influence of impaired hemodynamics on the blood oxygenation level dependent (BOLD) response. In both patients no structural lesions were present in primary motor pathways. A redistribution of the motor network to the healthy hemisphere was the main indicator of chronic hemodynamic compromise.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Chronic Disease
  • Efferent Pathways / pathology
  • Efferent Pathways / physiopathology
  • Female
  • Functional Laterality
  • Gadolinium DTPA
  • Hemodynamics*
  • Humans
  • Infarction, Middle Cerebral Artery / complications
  • Infarction, Middle Cerebral Artery / diagnosis*
  • Infarction, Middle Cerebral Artery / physiopathology*
  • Ischemic Attack, Transient / diagnosis
  • Ischemic Attack, Transient / etiology
  • Ischemic Attack, Transient / physiopathology
  • Magnetic Resonance Angiography
  • Magnetic Resonance Imaging
  • Male
  • Nerve Net / pathology
  • Nerve Net / physiopathology*
  • Recurrence
  • Reference Values

Substances

  • Gadolinium DTPA