A case of a 45-year-old male patient with hypertrophic cardiomyopathy (HCM) is presented. The patient suffered from chest pain since his childhood. He was hospitalised several times but accurate diagnosis was not established for nearly 20 years. The ECG changes were interpreted as myocardial ischaemia. The proper diagnosis was based on echocardiographic and catheterisation data. Nowadays, echocardiography is the method of choice in the detection of HCM. HCM is an important cause of chest pain, especially in young patients.