Abstract
A 71-year-old man underwent low anterior resection for rectal cancer. Two years after the surgery, liver metastasis and local recurrence were found on the CT scan. The first-line treatment was systemic chemotherapy (CPT-11 and 5'-DFUR). Effect was satisfactory for local recurrence, but a new liver tumor was found on the CT scan. The second-line treatment was a hepatic arterial infusion (5-FU) and systemic chemotherapy (UFT). After 4 courses, the liver metastasis was reduced, but after 5 courses, the liver tumors had enlarged. The third-line treatment was a hepatic arterial infusion (5-FU + levofolinate) and systemic chemotherapy (UFT). After 5 courses, the liver tumor disappeared, and no other recurrence was found on the CT scan.
MeSH terms
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Adenocarcinoma / drug therapy*
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Adenocarcinoma / secondary
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Aged
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Antineoplastic Combined Chemotherapy Protocols / therapeutic use*
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Camptothecin / administration & dosage
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Camptothecin / analogs & derivatives*
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Drug Administration Schedule
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Drug Combinations
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Floxuridine / administration & dosage
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Fluorouracil / administration & dosage
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Hepatic Artery
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Humans
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Infusions, Intra-Arterial
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Irinotecan
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Leucovorin / administration & dosage
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Liver Neoplasms / drug therapy*
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Liver Neoplasms / secondary
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Male
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Neoplasm Recurrence, Local / drug therapy*
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Rectal Neoplasms / pathology*
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Rectal Neoplasms / surgery
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Tegafur / administration & dosage
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Uracil / administration & dosage
Substances
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Drug Combinations
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UFT(R) drug
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Floxuridine
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Tegafur
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Uracil
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Irinotecan
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Leucovorin
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Fluorouracil
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doxifluridine
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Camptothecin