Abstract
The patient was a 74-year-old woman with gastric cancer with multiple liver metastasis. She was treated with daily oral administration of TS-1 100 mg/day (day 1-21) and systemic administration of CDDP 90 mg (day 8) as neoadjuvant chemotherapy for 2 courses. As metastatic lesions became smaller, we performed distal gastrectomy. TS-1 was started for the residual cancer lesion. However, liver metastatic lesions increased in size, so we carried out intraarterial chemotherapy (IAC), Nausea appeared at 9 days, pancytopenia at 28 days and ARDS at 78 days after IAC. She died due to ARDS.
MeSH terms
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Aged
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Antimetabolites, Antineoplastic / administration & dosage
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Antimetabolites, Antineoplastic / adverse effects*
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Cisplatin / administration & dosage
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Drug Combinations
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Female
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Fluorouracil / administration & dosage
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Fluorouracil / adverse effects*
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Gastrectomy
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Hepatic Artery
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Humans
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Infusions, Intra-Arterial
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Liver Neoplasms / drug therapy
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Liver Neoplasms / secondary
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Oxonic Acid / administration & dosage
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Pancytopenia / chemically induced*
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Pyridines / administration & dosage
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Respiratory Distress Syndrome / chemically induced*
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Stomach Neoplasms / drug therapy*
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Stomach Neoplasms / pathology
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Stomach Neoplasms / surgery
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Tegafur / administration & dosage
Substances
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Antimetabolites, Antineoplastic
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Drug Combinations
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Pyridines
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S 1 (combination)
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Tegafur
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Oxonic Acid
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Cisplatin
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Fluorouracil