Usefulness of coronary flow reserve measured by transthoracic coronary Doppler ultrasound to detect severe left anterior descending coronary artery stenosis

Paolo Voci; Francesco Pizzuto; Enrica Mariano; Paolo Emilio Puddu; Gennaro Sardella; Francesco Romeo

doi:10.1016/j.amjcard.2003.08.016

Usefulness of coronary flow reserve measured by transthoracic coronary Doppler ultrasound to detect severe left anterior descending coronary artery stenosis

Am J Cardiol. 2003 Dec 1;92(11):1320-4. doi: 10.1016/j.amjcard.2003.08.016.

Authors

Paolo Voci¹, Francesco Pizzuto, Enrica Mariano, Paolo Emilio Puddu, Gennaro Sardella, Francesco Romeo

Affiliation

¹ University of Rome La Sapienza, Rome, Italy. [email protected]

PMID: 14636912
DOI: 10.1016/j.amjcard.2003.08.016

Abstract

Transthoracic coronary Doppler ultrasound during venous adenosine infusion showed damped (<1) coronary flow velocity reserve in patients with severe left anterior descending coronary artery stenosis. Damped coronary flow reserve discriminated severe from nonsevere stenosis with high sensitivity, specificity, and positive predictive accuracy, and is a unique noninvasive tool to identify high-risk patients.

MeSH terms

Adenosine / administration & dosage
Aged
Analysis of Variance
Blood Flow Velocity
Chi-Square Distribution
Coronary Circulation / physiology*
Coronary Stenosis / diagnostic imaging*
Coronary Stenosis / physiopathology*
Echocardiography / methods
Female
Humans
Infusions, Intravenous
Male
Middle Aged
Predictive Value of Tests
Sensitivity and Specificity
Vasodilator Agents / administration & dosage

Substances

Vasodilator Agents
Adenosine